I apologize for not listing more details in the original post, and I'll address each point below.
Toxicity:
Yes this one is a MAJOR concern of mine. It very much would require a lab to assist in it's development (mostly in glycoalkaloids measurements, possible gene deactivation, but that's only if a outside source would find interest in the project). My goal/ hope is that I can somehow breed the plant to no longer produce solanine in the tubers or fruit, but instead take after it's tomato heritage and produce tomatine up until the fruit/tubers are ripe to eat allowing it to be safer than standard potatoes.
Fruiting & tuber sizes:
Fortunately there is a much simpler way to deal with this than with the concerns of toxicity. The plant would need to be based on a determinate or semi-determinate design. This would optimize the plants to focus more energy into food production (and hopefully will allow the plants to mature earlier) as apposed to plant growth seen in indeterminates.
for the plants themselves they can be divided into three categories of production (based of fruit)
Cherry: small 2oz fruit, but can yield larger tuber sizes *starch potatoes*
Mid: Medium 5-8 oz fruit, but can yield medium tuber sizes *new potatoes*
Full: Large 10+oz fruit, but can yield small tuber sizes *fingerlings potatoes*
Hopefully by compartmentalizing this hybrid into these subcategories it will avoid any potential stress or confusion for the plants. It very much needs to be a finely tuned balancing act for it to achieve it's fullest potential.
As for the papers listed below I actually have read them before partially the reason I got inspired to do said project, but I never thought about contacting them. Probably would be good idea. Thanks! I'll send them a email come Monday afternoon